| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| D5446 | 镇江 | 07:07 | 扬州东 | 07:36 |
| D5447 | 镇江 | 07:07 | 扬州东 | 07:36 |
| D5492 | 镇江 | 08:04 | 扬州东 | 08:33 |
| D5472 | 镇江 | 08:51 | 扬州东 | 09:31 |
| D5473 | 镇江 | 08:51 | 扬州东 | 09:31 |
| D2106 | 镇江 | 10:08 | 扬州东 | 10:39 |
| D2107 | 镇江 | 10:08 | 扬州东 | 10:39 |
| D5454 | 镇江 | 10:16 | 扬州东 | 10:45 |
| D5455 | 镇江 | 10:16 | 扬州东 | 10:45 |
| D5426 | 镇江 | 11:52 | 扬州东 | 12:22 |
| D5427 | 镇江 | 11:52 | 扬州东 | 12:22 |
| D5458 | 镇江 | 12:09 | 扬州东 | 12:45 |
| D3185 | 镇江 | 12:28 | 扬州东 | 12:57 |
| D3188 | 镇江 | 12:28 | 扬州东 | 12:57 |
| D5402 | 镇江 | 12:52 | 扬州东 | 13:22 |
| D5403 | 镇江 | 12:52 | 扬州东 | 13:22 |
| D5406 | 镇江 | 13:32 | 扬州东 | 14:01 |
| D5407 | 镇江 | 13:32 | 扬州东 | 14:01 |
| D5430 | 镇江 | 14:38 | 扬州东 | 15:07 |
| D5431 | 镇江 | 14:38 | 扬州东 | 15:07 |
| D5522 | 镇江 | 14:51 | 扬州东 | 15:20 |
| D5523 | 镇江 | 14:51 | 扬州东 | 15:20 |
| D5451 | 镇江 | 15:11 | 扬州东 | 15:41 |
| D2874 | 镇江 | 15:38 | 扬州东 | 16:07 |
| D2875 | 镇江 | 15:38 | 扬州东 | 16:07 |
| D373 | 镇江 | 15:49 | 扬州东 | 16:18 |
| D376 | 镇江 | 15:49 | 扬州东 | 16:18 |
| D5526 | 镇江 | 16:56 | 扬州东 | 17:26 |
| D5527 | 镇江 | 16:56 | 扬州东 | 17:26 |
| D5466 | 镇江 | 17:07 | 扬州东 | 17:36 |
| D5467 | 镇江 | 17:07 | 扬州东 | 17:36 |
| D5434 | 镇江 | 17:43 | 扬州东 | 18:13 |
| D5435 | 镇江 | 17:43 | 扬州东 | 18:13 |
| D5510 | 镇江 | 17:53 | 扬州东 | 18:29 |
| D5511 | 镇江 | 17:53 | 扬州东 | 18:29 |
| D5502 | 镇江 | 18:27 | 扬州东 | 18:56 |
| D5503 | 镇江 | 18:27 | 扬州东 | 18:56 |
| D2896 | 镇江 | 18:50 | 扬州东 | 19:19 |
| D2897 | 镇江 | 18:50 | 扬州东 | 19:19 |
| D5506 | 镇江 | 19:43 | 扬州东 | 20:12 |
| D5507 | 镇江 | 19:43 | 扬州东 | 20:12 |
| D3151 | 镇江 | 19:55 | 扬州东 | 20:30 |
| D3154 | 镇江 | 19:55 | 扬州东 | 20:30 |
| D5442 | 镇江 | 20:04 | 扬州东 | 20:35 |
| D5443 | 镇江 | 20:04 | 扬州东 | 20:35 |
| D5438 | 镇江 | 20:17 | 扬州东 | 20:46 |
| D5439 | 镇江 | 20:17 | 扬州东 | 20:46 |
| D5516 | 镇江 | 21:19 | 扬州东 | 21:49 |
| D5517 | 镇江 | 21:19 | 扬州东 | 21:49 |