| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| G5400 | 贵阳北 | 07:01 | 三穗 | 08:03 |
| G2361 | 贵阳北 | 07:24 | 三穗 | 08:26 |
| G2364 | 贵阳北 | 07:24 | 三穗 | 08:26 |
| G2116 | 贵阳北 | 08:14 | 三穗 | 09:23 |
| G2194 | 贵阳东 | 09:43 | 三穗 | 10:41 |
| G2195 | 贵阳东 | 09:43 | 三穗 | 10:41 |
| G2370 | 贵阳东 | 10:24 | 三穗 | 11:31 |
| G2371 | 贵阳东 | 10:24 | 三穗 | 11:31 |
| G1538 | 贵阳北 | 11:22 | 三穗 | 12:28 |
| G1752 | 贵阳北 | 12:36 | 三穗 | 13:39 |
| G1753 | 贵阳北 | 12:36 | 三穗 | 13:39 |
| G1539 | 贵阳北 | 12:46 | 三穗 | 13:50 |
| G2186 | 贵阳东 | 13:25 | 三穗 | 14:23 |
| G2187 | 贵阳东 | 13:25 | 三穗 | 14:23 |
| G2166 | 贵阳东 | 16:58 | 三穗 | 17:57 |
| G2167 | 贵阳东 | 16:58 | 三穗 | 17:57 |
| G2126 | 贵阳北 | 18:29 | 三穗 | 19:32 |
| G2127 | 贵阳北 | 18:29 | 三穗 | 19:32 |