| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| G2301 | 宜宾 | 06:34 | 毕节 | 07:44 |
| G2304 | 宜宾 | 06:34 | 毕节 | 07:44 |
| G2194 | 宜宾西 | 07:32 | 毕节 | 08:52 |
| G2195 | 宜宾西 | 07:32 | 毕节 | 08:52 |
| D1833 | 宜宾 | 09:17 | 毕节 | 10:37 |
| G2277 | 宜宾西 | 09:29 | 毕节 | 10:54 |
| G2280 | 宜宾西 | 09:29 | 毕节 | 10:54 |
| G8787 | 宜宾西 | 09:48 | 毕节 | 11:02 |
| G8788 | 宜宾西 | 09:48 | 毕节 | 11:02 |
| D1791 | 宜宾西 | 10:46 | 毕节 | 11:52 |
| G2190 | 宜宾西 | 10:56 | 毕节 | 12:04 |
| G2191 | 宜宾西 | 10:56 | 毕节 | 12:04 |
| D5123 | 宜宾 | 12:34 | 毕节 | 14:07 |
| G8752 | 宜宾 | 14:20 | 毕节 | 15:24 |
| G8753 | 宜宾 | 14:20 | 毕节 | 15:24 |
| G2166 | 宜宾西 | 14:47 | 毕节 | 15:49 |
| G2167 | 宜宾西 | 14:47 | 毕节 | 15:49 |
| G8762 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8763 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8764 | 宜宾西 | 16:30 | 毕节 | 17:33 |
| G8765 | 宜宾西 | 16:30 | 毕节 | 17:33 |
| G2831 | 宜宾西 | 16:59 | 毕节 | 18:13 |
| G2829 | 宜宾西 | 17:14 | 毕节 | 18:28 |
| D1717 | 宜宾西 | 17:52 | 毕节 | 18:59 |
| G2827 | 宜宾 | 18:46 | 毕节 | 19:50 |
| D1708 | 宜宾西 | 18:54 | 毕节 | 20:01 |
| G2825 | 宜宾西 | 19:01 | 毕节 | 20:09 |