| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K282 | 蚌埠 | 02:58 | 开封 | 08:04 |
| K283 | 蚌埠 | 02:58 | 开封 | 08:04 |
| K4026 | 蚌埠 | 08:00 | 开封 | 14:02 |
| K4027 | 蚌埠 | 08:00 | 开封 | 14:02 |
| K4030 | 蚌埠 | 10:21 | 开封 | 17:30 |
| K4031 | 蚌埠 | 10:21 | 开封 | 17:30 |
| K4055 | 蚌埠 | 10:35 | 开封 | 17:15 |
| K4046 | 蚌埠 | 12:26 | 开封 | 18:46 |
| K2186 | 蚌埠 | 15:02 | 开封 | 20:24 |
| K2187 | 蚌埠 | 15:02 | 开封 | 20:24 |
| K290 | 蚌埠 | 15:14 | 开封 | 20:55 |
| K291 | 蚌埠 | 15:14 | 开封 | 20:55 |
| K1147 | 蚌埠 | 15:21 | 开封 | 21:06 |
| K1150 | 蚌埠 | 15:21 | 开封 | 21:06 |
| K360 | 蚌埠 | 15:28 | 开封 | 21:42 |
| K361 | 蚌埠 | 15:28 | 开封 | 21:42 |
| G1822 | 蚌埠南 | 17:48 | 开封北 | 20:14 |
| G1823 | 蚌埠南 | 17:48 | 开封北 | 20:14 |
| K1102 | 蚌埠 | 21:00 | 开封 | 03:12 |
| K1103 | 蚌埠 | 21:00 | 开封 | 03:12 |
| Z40 | 蚌埠 | 21:30 | 开封 | 01:24 |
| Z41 | 蚌埠 | 21:30 | 开封 | 01:24 |
| K59 | 蚌埠 | 22:33 | 开封 | 05:44 |
| K62 | 蚌埠 | 22:33 | 开封 | 05:44 |