| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K282 | 蚌埠 | 02:58 | 开封 | 08:04 |
| K283 | 蚌埠 | 02:58 | 开封 | 08:04 |
| K4796 | 蚌埠 | 06:10 | 开封 | 11:14 |
| K4797 | 蚌埠 | 06:10 | 开封 | 11:14 |
| K4026 | 蚌埠 | 08:00 | 开封 | 13:49 |
| K4027 | 蚌埠 | 08:00 | 开封 | 13:49 |
| K4030 | 蚌埠 | 10:28 | 开封 | 17:11 |
| K4031 | 蚌埠 | 10:28 | 开封 | 17:11 |
| K4055 | 蚌埠 | 10:35 | 开封 | 17:24 |
| K4046 | 蚌埠 | 12:38 | 开封 | 18:46 |
| K2186 | 蚌埠 | 15:03 | 开封 | 20:15 |
| K2187 | 蚌埠 | 15:03 | 开封 | 20:15 |
| K290 | 蚌埠 | 15:14 | 开封 | 20:55 |
| K291 | 蚌埠 | 15:14 | 开封 | 20:55 |
| K1147 | 蚌埠 | 15:21 | 开封 | 21:09 |
| K1150 | 蚌埠 | 15:21 | 开封 | 21:09 |
| K360 | 蚌埠 | 15:28 | 开封 | 21:45 |
| K361 | 蚌埠 | 15:28 | 开封 | 21:45 |
| G1822 | 蚌埠南 | 17:49 | 开封北 | 20:05 |
| G1823 | 蚌埠南 | 17:49 | 开封北 | 20:05 |
| K4666 | 蚌埠 | 18:48 | 开封 | 02:30 |
| K1102 | 蚌埠 | 20:57 | 开封 | 02:50 |
| K1103 | 蚌埠 | 20:57 | 开封 | 02:50 |
| Z40 | 蚌埠 | 21:30 | 开封 | 01:24 |
| Z41 | 蚌埠 | 21:30 | 开封 | 01:24 |
| K59 | 蚌埠 | 22:33 | 开封 | 05:42 |
| K62 | 蚌埠 | 22:33 | 开封 | 05:42 |