| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K4358 | 贵阳 | 05:10 | 镇远 | 10:21 |
| K740 | 贵阳 | 08:39 | 镇远 | 12:45 |
| K112 | 贵阳 | 09:00 | 镇远 | 13:14 |
| K942 | 贵阳 | 10:59 | 镇远 | 15:00 |
| K943 | 贵阳 | 10:59 | 镇远 | 15:00 |
| K4178 | 贵阳 | 11:55 | 镇远 | 16:39 |
| K4418 | 贵阳 | 12:34 | 镇远 | 17:09 |
| 5640 | 贵阳 | 13:02 | 镇远 | 18:26 |
| K516 | 贵阳 | 13:49 | 镇远 | 18:00 |
| K517 | 贵阳 | 13:49 | 镇远 | 18:00 |
| K4086 | 贵阳 | 13:56 | 镇远 | 19:01 |
| K876 | 贵阳 | 14:10 | 镇远 | 18:37 |
| K877 | 贵阳 | 14:10 | 镇远 | 18:37 |
| K4952 | 贵阳 | 15:22 | 镇远 | 19:39 |
| K4953 | 贵阳 | 15:22 | 镇远 | 19:39 |
| K4906 | 贵阳 | 17:16 | 镇远 | 21:36 |