| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K559 | 开封 | 01:07 | 蚌埠 | 06:22 |
| K2665 | 开封 | 01:37 | 蚌埠 | 06:34 |
| T114 | 开封 | 06:40 | 蚌埠 | 11:06 |
| K4190 | 开封 | 11:43 | 蚌埠 | 18:29 |
| G1972 | 开封北 | 16:44 | 蚌埠南 | 19:02 |
| G1976 | 开封北 | 17:45 | 蚌埠南 | 20:10 |
| K2188 | 开封 | 18:05 | 蚌埠 | 23:34 |
| K292 | 开封 | 18:29 | 蚌埠 | 23:40 |
| K154 | 开封 | 19:01 | 蚌埠 | 00:41 |
| K284 | 开封 | 20:12 | 蚌埠 | 01:24 |
| K1101 | 开封 | 20:23 | 蚌埠 | 02:09 |
| K1149 | 开封 | 20:44 | 蚌埠 | 02:02 |