| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K132 | 开封 | 07:46 | 阜阳 | 11:54 |
| K133 | 开封 | 07:46 | 阜阳 | 11:54 |
| G1869 | 开封北 | 08:04 | 阜阳西 | 09:40 |
| G1872 | 开封北 | 08:04 | 阜阳西 | 09:40 |
| G3113 | 开封北 | 08:52 | 阜阳西 | 10:27 |
| G3116 | 开封北 | 08:52 | 阜阳西 | 10:27 |
| K4161 | 开封 | 10:40 | 阜阳 | 14:06 |
| K4164 | 开封 | 10:40 | 阜阳 | 14:06 |
| G3151 | 开封北 | 11:28 | 阜阳西 | 13:06 |
| G3154 | 开封北 | 11:28 | 阜阳西 | 13:06 |
| G2387 | 开封北 | 11:53 | 阜阳西 | 13:39 |
| G2390 | 开封北 | 11:53 | 阜阳西 | 13:39 |
| K4361 | 开封 | 12:08 | 阜阳 | 16:10 |
| K4364 | 开封 | 12:08 | 阜阳 | 16:10 |
| K29 | 开封 | 15:53 | 阜阳 | 20:20 |
| K32 | 开封 | 15:53 | 阜阳 | 20:20 |
| T40 | 开封 | 16:04 | 阜阳 | 19:22 |
| G1943 | 开封北 | 17:30 | 阜阳西 | 19:22 |
| G1946 | 开封北 | 17:30 | 阜阳西 | 19:22 |
| G1877 | 开封北 | 19:07 | 阜阳西 | 20:43 |
| G1880 | 开封北 | 19:07 | 阜阳西 | 20:43 |
| D226 | 开封 | 19:33 | 阜阳 | 22:10 |
| D227 | 开封 | 19:33 | 阜阳 | 22:10 |
| K605 | 开封 | 22:21 | 阜阳 | 02:11 |
| K608 | 开封 | 22:21 | 阜阳 | 02:11 |
| K61 | 开封 | 23:26 | 阜阳 | 03:30 |
| K60 | 开封 | 23:26 | 阜阳 | 03:30 |
| K2275 | 开封 | 23:59 | 阜阳 | 03:39 |
| K2278 | 开封 | 23:59 | 阜阳 | 03:39 |