| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K132 | 开封 | 07:46 | 阜阳 | 11:54 |
| K133 | 开封 | 07:46 | 阜阳 | 11:54 |
| G1869 | 开封北 | 08:04 | 阜阳西 | 09:40 |
| G1872 | 开封北 | 08:04 | 阜阳西 | 09:40 |
| G3113 | 开封北 | 08:52 | 阜阳西 | 10:23 |
| G3116 | 开封北 | 08:52 | 阜阳西 | 10:23 |
| K4161 | 开封 | 10:01 | 阜阳 | 14:06 |
| K4164 | 开封 | 10:01 | 阜阳 | 14:06 |
| G2387 | 开封北 | 11:52 | 阜阳西 | 13:39 |
| G2390 | 开封北 | 11:52 | 阜阳西 | 13:39 |
| K4361 | 开封 | 12:10 | 阜阳 | 16:10 |
| K4364 | 开封 | 12:10 | 阜阳 | 16:10 |
| K1237 | 开封 | 15:45 | 阜阳 | 19:22 |
| K1240 | 开封 | 15:45 | 阜阳 | 19:22 |
| G1881 | 开封北 | 15:47 | 阜阳西 | 17:55 |
| G1884 | 开封北 | 15:47 | 阜阳西 | 17:55 |
| K29 | 开封 | 15:58 | 阜阳 | 20:20 |
| K32 | 开封 | 15:58 | 阜阳 | 20:20 |
| G1943 | 开封北 | 17:30 | 阜阳西 | 19:22 |
| G1946 | 开封北 | 17:30 | 阜阳西 | 19:22 |
| T325 | 开封 | 20:33 | 阜阳 | 23:43 |
| T328 | 开封 | 20:33 | 阜阳 | 23:43 |
| K605 | 开封 | 22:09 | 阜阳 | 02:11 |
| K608 | 开封 | 22:09 | 阜阳 | 02:11 |
| K61 | 开封 | 23:26 | 阜阳 | 03:30 |
| K60 | 开封 | 23:26 | 阜阳 | 03:30 |
| K2275 | 开封 | 23:59 | 阜阳 | 03:39 |
| K2278 | 开封 | 23:59 | 阜阳 | 03:39 |