| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K4026 | 上海 | 02:05 | 开封 | 14:02 |
| K4027 | 上海 | 02:05 | 开封 | 14:02 |
| K4030 | 上海 | 03:00 | 开封 | 17:30 |
| K4031 | 上海 | 03:00 | 开封 | 17:30 |
| K4055 | 上海 | 04:00 | 开封 | 17:15 |
| K4046 | 上海 | 04:52 | 开封 | 18:46 |
| G4298 | 上海虹桥 | 05:12 | 开封北 | 09:02 |
| G1974 | 上海虹桥 | 07:16 | 开封北 | 11:49 |
| G1975 | 上海虹桥 | 07:16 | 开封北 | 11:49 |
| K2186 | 上海 | 08:57 | 开封 | 20:24 |
| K2187 | 上海 | 08:57 | 开封 | 20:24 |
| K360 | 上海 | 09:29 | 开封 | 21:42 |
| K361 | 上海 | 09:29 | 开封 | 21:42 |
| G3284 | 上海虹桥 | 10:37 | 开封北 | 16:45 |
| G3285 | 上海虹桥 | 10:37 | 开封北 | 16:45 |
| K234 | 上海 | 11:10 | 开封 | 23:46 |
| K235 | 上海 | 11:10 | 开封 | 23:46 |
| K1102 | 上海 | 13:40 | 开封 | 03:12 |
| K1103 | 上海 | 13:40 | 开封 | 03:12 |
| G80 | 上海虹桥 | 14:04 | 开封北 | 17:41 |
| G81 | 上海虹桥 | 14:04 | 开封北 | 17:41 |
| D122 | 上海 | 14:13 | 开封 | 22:24 |
| D123 | 上海 | 14:13 | 开封 | 22:24 |
| G1818 | 上海虹桥 | 14:33 | 开封北 | 18:59 |
| G1819 | 上海虹桥 | 14:33 | 开封北 | 18:59 |
| G1822 | 上海虹桥 | 15:32 | 开封北 | 20:14 |
| G1823 | 上海虹桥 | 15:32 | 开封北 | 20:14 |
| K557 | 上海 | 15:52 | 开封 | 04:27 |
| K560 | 上海 | 15:52 | 开封 | 04:27 |
| G2612 | 上海虹桥 | 15:53 | 开封北 | 21:37 |
| G2613 | 上海虹桥 | 15:53 | 开封北 | 21:37 |
| Z40 | 上海 | 16:48 | 开封 | 01:24 |
| Z41 | 上海 | 16:48 | 开封 | 01:24 |
| K282 | 上海 | 20:45 | 开封 | 08:04 |
| K283 | 上海 | 20:45 | 开封 | 08:04 |