| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| D5401 | 宿迁 | 06:40 | 镇江 | 08:24 |
| D5404 | 宿迁 | 06:40 | 镇江 | 08:24 |
| D5405 | 宿迁 | 09:54 | 镇江 | 11:48 |
| D5408 | 宿迁 | 09:54 | 镇江 | 11:48 |
| D5409 | 宿迁 | 11:16 | 镇江 | 13:02 |
| D5412 | 宿迁 | 11:16 | 镇江 | 13:02 |
| D5413 | 宿迁 | 13:43 | 镇江 | 15:47 |
| D5416 | 宿迁 | 13:43 | 镇江 | 15:47 |
| D5417 | 宿迁 | 14:53 | 镇江 | 16:53 |
| G8381 | 宿迁 | 17:52 | 镇江 | 19:28 |
| G8384 | 宿迁 | 17:52 | 镇江 | 19:28 |
| D5471 | 宿迁 | 20:10 | 镇江 | 21:51 |
| D5474 | 宿迁 | 20:10 | 镇江 | 21:51 |