| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| D5151 | 宜宾西 | 07:52 | 毕节 | 09:09 |
| D5181 | 宜宾西 | 07:52 | 毕节 | 09:09 |
| G8761 | 宜宾 | 07:56 | 毕节 | 08:59 |
| G2277 | 宜宾西 | 09:23 | 毕节 | 10:47 |
| G2280 | 宜宾西 | 09:23 | 毕节 | 10:47 |
| G8787 | 宜宾西 | 09:52 | 毕节 | 11:00 |
| G8788 | 宜宾西 | 09:52 | 毕节 | 11:00 |
| G8793 | 宜宾西 | 09:52 | 毕节 | 11:00 |
| G8794 | 宜宾西 | 09:52 | 毕节 | 11:00 |
| D1801 | 宜宾西 | 10:10 | 毕节 | 11:57 |
| D1791 | 宜宾西 | 10:33 | 毕节 | 11:40 |
| G2190 | 宜宾西 | 11:02 | 毕节 | 12:10 |
| G2191 | 宜宾西 | 11:02 | 毕节 | 12:10 |
| D1809 | 宜宾西 | 11:48 | 毕节 | 12:55 |
| G8752 | 宜宾 | 14:18 | 毕节 | 15:23 |
| G8753 | 宜宾 | 14:18 | 毕节 | 15:23 |
| C6053 | 宜宾 | 14:36 | 毕节 | 15:44 |
| D8557 | 宜宾西 | 14:45 | 毕节 | 15:57 |
| G2166 | 宜宾西 | 14:53 | 毕节 | 16:07 |
| G2167 | 宜宾西 | 14:53 | 毕节 | 16:07 |
| G8762 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8763 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8768 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8769 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8521 | 宜宾 | 16:17 | 毕节 | 17:38 |
| G2831 | 宜宾西 | 16:52 | 毕节 | 18:00 |
| G2829 | 宜宾西 | 17:12 | 毕节 | 18:29 |
| D1717 | 宜宾西 | 17:54 | 毕节 | 19:21 |
| G2182 | 宜宾西 | 18:02 | 毕节 | 19:04 |
| G2183 | 宜宾西 | 18:02 | 毕节 | 19:04 |
| C6383 | 宜宾 | 18:08 | 毕节 | 19:29 |
| G4537 | 宜宾 | 18:50 | 毕节 | 19:55 |
| G2825 | 宜宾西 | 19:01 | 毕节 | 20:09 |
| G5359 | 宜宾西 | 20:43 | 毕节 | 21:45 |
| D4283 | 宜宾西 | 21:20 | 毕节 | 22:27 |