| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| G2301 | 宜宾 | 06:34 | 毕节 | 07:44 |
| G2304 | 宜宾 | 06:34 | 毕节 | 07:44 |
| G2194 | 宜宾西 | 07:38 | 毕节 | 08:52 |
| G2195 | 宜宾西 | 07:38 | 毕节 | 08:52 |
| D1833 | 宜宾 | 09:17 | 毕节 | 10:37 |
| G2277 | 宜宾西 | 09:29 | 毕节 | 10:48 |
| G2280 | 宜宾西 | 09:29 | 毕节 | 10:48 |
| G8787 | 宜宾西 | 09:54 | 毕节 | 11:02 |
| G8788 | 宜宾西 | 09:54 | 毕节 | 11:02 |
| D1791 | 宜宾西 | 10:46 | 毕节 | 11:52 |
| G2190 | 宜宾 | 10:54 | 毕节 | 12:04 |
| G2191 | 宜宾 | 10:54 | 毕节 | 12:04 |
| D1801 | 宜宾西 | 11:02 | 毕节 | 12:15 |
| D1809 | 宜宾西 | 11:48 | 毕节 | 12:55 |
| D5123 | 宜宾 | 12:34 | 毕节 | 14:07 |
| G8752 | 宜宾 | 14:20 | 毕节 | 15:24 |
| G8753 | 宜宾 | 14:20 | 毕节 | 15:24 |
| G2166 | 宜宾西 | 14:53 | 毕节 | 16:07 |
| G2167 | 宜宾西 | 14:53 | 毕节 | 16:07 |
| G8762 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8763 | 宜宾西 | 15:25 | 毕节 | 16:27 |
| G8764 | 宜宾西 | 16:25 | 毕节 | 17:33 |
| G8765 | 宜宾西 | 16:25 | 毕节 | 17:33 |
| G4787 | 宜宾 | 16:36 | 毕节 | 17:51 |
| D4973 | 宜宾 | 16:44 | 毕节 | 17:58 |
| G2831 | 宜宾西 | 16:58 | 毕节 | 18:06 |
| G2829 | 宜宾西 | 17:14 | 毕节 | 18:28 |
| D1717 | 宜宾西 | 17:53 | 毕节 | 19:21 |
| G2182 | 宜宾西 | 18:02 | 毕节 | 19:04 |
| G2183 | 宜宾西 | 18:02 | 毕节 | 19:04 |
| G4678 | 宜宾西 | 18:26 | 毕节 | 19:29 |
| G4925 | 宜宾 | 18:37 | 毕节 | 19:48 |
| D1708 | 宜宾西 | 18:50 | 毕节 | 20:03 |
| G2825 | 宜宾西 | 19:01 | 毕节 | 20:09 |
| D4329 | 宜宾西 | 19:06 | 毕节 | 20:26 |
| G4783 | 宜宾 | 19:10 | 毕节 | 20:14 |
| C5997 | 宜宾西 | 19:34 | 毕节 | 20:59 |
| D4017 | 宜宾西 | 20:07 | 毕节 | 21:14 |
| G4069 | 宜宾西 | 20:26 | 毕节 | 21:42 |
| D4729 | 宜宾 | 22:30 | 毕节 | 23:38 |