| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K4026 | 镇江 | 04:58 | 开封 | 13:49 |
| K4027 | 镇江 | 04:58 | 开封 | 13:49 |
| K4030 | 镇江 | 06:26 | 开封 | 17:11 |
| K4031 | 镇江 | 06:26 | 开封 | 17:11 |
| K4046 | 镇江 | 08:44 | 开封 | 18:46 |
| K2186 | 镇江 | 11:52 | 开封 | 20:15 |
| K2187 | 镇江 | 11:52 | 开封 | 20:15 |
| K360 | 镇江 | 12:18 | 开封 | 21:45 |
| K361 | 镇江 | 12:18 | 开封 | 21:45 |
| G3152 | 镇江南 | 12:56 | 开封北 | 17:49 |
| G3153 | 镇江南 | 12:56 | 开封北 | 17:49 |
| G1818 | 镇江南 | 15:45 | 开封北 | 18:59 |
| G1819 | 镇江南 | 15:45 | 开封北 | 18:59 |
| K557 | 镇江 | 18:46 | 开封 | 04:27 |
| K560 | 镇江 | 18:46 | 开封 | 04:27 |