| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| D5401 | 扬州东 | 07:53 | 镇江 | 08:24 |
| D5404 | 扬州东 | 07:53 | 镇江 | 08:24 |
| D374 | 扬州东 | 08:53 | 镇江 | 09:28 |
| D375 | 扬州东 | 08:53 | 镇江 | 09:28 |
| D3152 | 扬州东 | 09:31 | 镇江 | 10:01 |
| D3153 | 扬州东 | 09:31 | 镇江 | 10:01 |
| D5421 | 扬州东 | 09:40 | 镇江 | 10:10 |
| D5424 | 扬州东 | 09:40 | 镇江 | 10:10 |
| D5441 | 扬州东 | 09:50 | 镇江 | 10:20 |
| D5444 | 扬州东 | 09:50 | 镇江 | 10:20 |
| D2895 | 扬州东 | 10:03 | 镇江 | 10:32 |
| D2898 | 扬州东 | 10:03 | 镇江 | 10:32 |
| D5501 | 扬州东 | 11:06 | 镇江 | 11:35 |
| D5504 | 扬州东 | 11:06 | 镇江 | 11:35 |
| D5405 | 扬州东 | 11:13 | 镇江 | 11:48 |
| D5408 | 扬州东 | 11:13 | 镇江 | 11:48 |
| D5453 | 扬州东 | 12:14 | 镇江 | 12:50 |
| D5456 | 扬州东 | 12:14 | 镇江 | 12:50 |
| D5409 | 扬州东 | 12:30 | 镇江 | 13:02 |
| D5412 | 扬州东 | 12:30 | 镇江 | 13:02 |
| D2873 | 扬州东 | 12:53 | 镇江 | 13:29 |
| D2876 | 扬州东 | 12:53 | 镇江 | 13:29 |
| D5445 | 扬州东 | 13:15 | 镇江 | 13:50 |
| D5448 | 扬州东 | 13:15 | 镇江 | 13:50 |
| D5505 | 扬州东 | 13:35 | 镇江 | 14:10 |
| D5508 | 扬州东 | 13:35 | 镇江 | 14:10 |
| D5509 | 扬州东 | 14:10 | 镇江 | 14:47 |
| D5512 | 扬州东 | 14:10 | 镇江 | 14:47 |
| D5457 | 扬州东 | 14:34 | 镇江 | 15:03 |
| D5413 | 扬州东 | 15:18 | 镇江 | 15:47 |
| D5416 | 扬州东 | 15:18 | 镇江 | 15:47 |
| D5429 | 扬州东 | 15:27 | 镇江 | 15:56 |
| D5432 | 扬州东 | 15:27 | 镇江 | 15:56 |
| D2865 | 扬州东 | 17:11 | 镇江 | 17:41 |
| D2868 | 扬州东 | 17:11 | 镇江 | 17:41 |
| D5465 | 扬州东 | 18:26 | 镇江 | 18:56 |
| D5468 | 扬州东 | 18:26 | 镇江 | 18:56 |
| D5521 | 扬州东 | 19:43 | 镇江 | 20:13 |
| D5524 | 扬州东 | 19:43 | 镇江 | 20:13 |
| D2869 | 扬州东 | 20:07 | 镇江 | 20:44 |
| D2872 | 扬州东 | 20:07 | 镇江 | 20:44 |
| D2105 | 扬州东 | 20:48 | 镇江 | 21:17 |
| D2108 | 扬州东 | 20:48 | 镇江 | 21:17 |
| D5491 | 扬州东 | 20:59 | 镇江 | 21:28 |
| D5494 | 扬州东 | 20:59 | 镇江 | 21:28 |
| D5471 | 扬州东 | 21:22 | 镇江 | 21:51 |
| D5474 | 扬州东 | 21:22 | 镇江 | 21:51 |
| D5452 | 扬州东 | 21:29 | 镇江 | 22:01 |