| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| G8752 | 贵阳北 | 09:42 | 毕节 | 15:24 |
| G8753 | 贵阳北 | 09:42 | 毕节 | 15:24 |
| G2832 | 贵阳北 | 09:43 | 毕节 | 10:31 |
| G8764 | 贵阳北 | 10:42 | 毕节 | 17:33 |
| G8765 | 贵阳北 | 10:42 | 毕节 | 17:33 |
| G8789 | 贵阳北 | 12:38 | 毕节 | 13:25 |
| G8790 | 贵阳北 | 12:38 | 毕节 | 13:25 |
| G2185 | 贵阳东 | 16:22 | 毕节 | 17:07 |
| G2188 | 贵阳东 | 16:22 | 毕节 | 17:07 |
| G2189 | 贵阳东 | 16:46 | 毕节 | 17:31 |
| G2192 | 贵阳东 | 16:46 | 毕节 | 17:31 |
| G3704 | 贵阳东 | 17:07 | 毕节 | 18:11 |
| G2306 | 贵阳东 | 17:27 | 毕节 | 18:24 |
| G2307 | 贵阳东 | 17:27 | 毕节 | 18:24 |
| G2278 | 贵阳东 | 18:07 | 毕节 | 18:58 |
| G2279 | 贵阳东 | 18:07 | 毕节 | 18:58 |
| G2302 | 贵阳东 | 19:09 | 毕节 | 19:54 |
| G2303 | 贵阳东 | 19:09 | 毕节 | 19:54 |
| G8526 | 贵阳 | 19:19 | 毕节 | 20:36 |
| G8526 | 贵阳北 | 19:41 | 毕节 | 20:36 |
| G2193 | 贵阳东 | 19:48 | 毕节 | 20:45 |
| G2196 | 贵阳东 | 19:48 | 毕节 | 20:45 |
| G2971 | 贵阳东 | 20:04 | 毕节 | 20:55 |
| G2974 | 贵阳东 | 20:04 | 毕节 | 20:55 |
| G3706 | 贵阳东 | 20:56 | 毕节 | 21:42 |