| 车次 | 出发站 | 开车时间 | 到达站 | 到达时间 |
| K740 | 曲靖 | 01:19 | 贵阳 | 08:24 |
| K4418 | 曲靖 | 01:54 | 贵阳 | 12:14 |
| G1380 | 曲靖北 | 08:01 | 贵阳北 | 09:57 |
| G2822 | 曲靖北 | 08:11 | 贵阳北 | 10:09 |
| Z54 | 曲靖 | 08:20 | 贵阳 | 13:35 |
| G2886 | 曲靖北 | 08:22 | 贵阳北 | 10:19 |
| G2892 | 曲靖北 | 08:34 | 贵阳北 | 10:24 |
| K4906 | 曲靖 | 08:40 | 贵阳 | 16:48 |
| G2872 | 曲靖北 | 08:43 | 贵阳北 | 10:49 |
| G2894 | 曲靖北 | 08:48 | 贵阳北 | 10:54 |
| G1682 | 曲靖北 | 08:53 | 贵阳北 | 11:04 |
| G1683 | 曲靖北 | 08:53 | 贵阳北 | 11:04 |
| G1538 | 曲靖北 | 08:58 | 贵阳北 | 11:15 |
| G2935 | 曲靖北 | 09:05 | 贵阳北 | 10:59 |
| G2938 | 曲靖北 | 09:05 | 贵阳北 | 10:59 |
| G2921 | 曲靖北 | 09:10 | 贵阳北 | 11:09 |
| G2924 | 曲靖北 | 09:10 | 贵阳北 | 11:09 |
| G2830 | 曲靖北 | 09:15 | 贵阳北 | 11:33 |
| G1392 | 曲靖北 | 09:34 | 贵阳北 | 11:44 |
| G1398 | 曲靖北 | 10:05 | 贵阳北 | 12:11 |
| G2868 | 曲靖北 | 10:22 | 贵阳北 | 12:22 |
| G1752 | 曲靖北 | 10:30 | 贵阳北 | 12:32 |
| G1753 | 曲靖北 | 10:30 | 贵阳北 | 12:32 |
| G1539 | 曲靖北 | 10:35 | 贵阳北 | 12:37 |
| G1372 | 曲靖北 | 10:41 | 贵阳北 | 12:42 |
| G3474 | 曲靖北 | 10:46 | 贵阳北 | 12:51 |
| G2828 | 曲靖北 | 10:58 | 贵阳北 | 12:57 |
| G980 | 曲靖北 | 11:12 | 贵阳北 | 13:39 |
| Z288 | 曲靖 | 11:29 | 贵阳 | 16:39 |
| Z289 | 曲靖 | 11:29 | 贵阳 | 16:39 |
| G2826 | 曲靖北 | 11:38 | 贵阳北 | 13:44 |
| G2852 | 曲靖北 | 11:53 | 贵阳北 | 13:59 |
| G1536 | 曲靖北 | 12:04 | 贵阳北 | 14:19 |
| G3472 | 曲靖北 | 12:17 | 贵阳北 | 14:09 |
| G1422 | 曲靖北 | 12:27 | 贵阳北 | 14:42 |
| K1236 | 曲靖 | 12:58 | 贵阳 | 19:37 |
| G2847 | 曲靖北 | 13:06 | 贵阳北 | 15:06 |
| G2850 | 曲靖北 | 13:06 | 贵阳北 | 15:06 |
| G2978 | 曲靖北 | 13:18 | 贵阳北 | 15:31 |
| G2890 | 曲靖北 | 13:47 | 贵阳北 | 15:38 |
| K492 | 曲靖 | 14:22 | 贵阳 | 20:20 |
| K493 | 曲靖 | 14:22 | 贵阳 | 20:20 |
| G2866 | 曲靖北 | 15:01 | 贵阳北 | 17:06 |
| G2884 | 曲靖北 | 15:40 | 贵阳北 | 17:46 |
| G2880 | 曲靖北 | 16:05 | 贵阳北 | 18:07 |
| G2126 | 曲靖北 | 16:19 | 贵阳东 | 18:32 |
| G2127 | 曲靖北 | 16:19 | 贵阳东 | 18:32 |
| G2802 | 曲靖北 | 16:31 | 贵阳北 | 18:30 |
| G1514 | 曲靖北 | 16:37 | 贵阳北 | 18:36 |
| G2925 | 曲靖北 | 16:42 | 贵阳北 | 18:41 |
| G2928 | 曲靖北 | 16:42 | 贵阳北 | 18:41 |
| G2122 | 曲靖北 | 17:08 | 贵阳北 | 19:11 |
| G2835 | 曲靖北 | 17:22 | 贵阳北 | 19:22 |
| G2838 | 曲靖北 | 17:22 | 贵阳北 | 19:22 |
| G2882 | 曲靖北 | 17:35 | 贵阳北 | 19:27 |
| G2876 | 曲靖北 | 18:06 | 贵阳东 | 20:25 |
| G4721 | 曲靖北 | 18:24 | 贵阳北 | 20:29 |
| G4724 | 曲靖北 | 18:24 | 贵阳北 | 20:29 |
| K138 | 曲靖 | 20:10 | 贵阳 | 02:19 |
| K80 | 曲靖 | 20:33 | 贵阳 | 02:27 |
| K986 | 曲靖 | 21:04 | 贵阳 | 03:44 |
| K987 | 曲靖 | 21:04 | 贵阳 | 03:44 |
| Z162 | 曲靖 | 21:21 | 贵阳 | 02:34 |
| G2982 | 曲靖北 | 21:26 | 贵阳北 | 23:32 |
| K4358 | 曲靖 | 21:33 | 贵阳 | 04:46 |
| K692 | 曲靖 | 22:01 | 贵阳 | 04:57 |
| G4900 | 曲靖北 | 23:23 | 贵阳北 | 01:15 |